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Tuesday, January 26, 2010

Making Sense of the Neandertal Genome | Genome Technology | Sequencing | GenomeWeb

Making Sense of the Neandertal Genome | Genome Technology | Sequencing | GenomeWeb
by Ciara Curtin
"Ed Green fell into studying the Neandertal genome. He'd arrived at the Max Planck Institute in Leipzig ready to dive into a study of alternative splicing in primates. Instead, he took on sequencing the Neandertal. '[I] just happened to be at the right place at the right time with the right skill set to look at the Neandertals as this high-throughput sequencing technology was coming online,' he says. And, of course, he says it's a really interesting project.

So far, the Neandertal Genome Project has reached a little more than one-fold coverage of the genome. The challenge now, Green says, is making sense of all that next-gen sequence data...."